Testicular reserve of testosterone precursors in primary testicular failure
AR Glass, RA Vigersky - Fertility and sterility, 1982 - Elsevier
To explore the abnormal steroidogenesis in subjects with primary testicular failure, we
measured serum levels of testosterone (T) and its precursors androstenedione (Δ 4 A) and
17-hydroxyprogesterone (17-OHP) in the basal state and after stimulation by human
chorionic gonadotropin (hCG) for 4 hours (acute reserve) or 72 hours (chronic reserve).
Subjects with primary testicular failure had decreased mean basal serum T, decreased
mean chronic T reserve, and absent mean acute T reserve. In contrast, these subjects had …
measured serum levels of testosterone (T) and its precursors androstenedione (Δ 4 A) and
17-hydroxyprogesterone (17-OHP) in the basal state and after stimulation by human
chorionic gonadotropin (hCG) for 4 hours (acute reserve) or 72 hours (chronic reserve).
Subjects with primary testicular failure had decreased mean basal serum T, decreased
mean chronic T reserve, and absent mean acute T reserve. In contrast, these subjects had …