Sex hormones, obesity, fat distribution, type 2 diabetes and insulin resistance: epidemiological and clinical correlation
SM Haffner - International Journal of Obesity, 2000 - nature.com
SM Haffner
International Journal of Obesity, 2000•nature.comIncreased androgenicity as assessed by increased testosterone and decreased SHBG is
strongly associated with an unfavorable body fat distribution and increased glucose and
insulin concentrations and insulin resistance in both pre-and postmenopausal women.
However, the temporal direction of the association between androgens and insulin is
uncertain. In men, the association between SHBG and insulin levels is much weaker and is
probably inverse.
strongly associated with an unfavorable body fat distribution and increased glucose and
insulin concentrations and insulin resistance in both pre-and postmenopausal women.
However, the temporal direction of the association between androgens and insulin is
uncertain. In men, the association between SHBG and insulin levels is much weaker and is
probably inverse.
Abstract
Increased androgenicity as assessed by increased testosterone and decreased SHBG is strongly associated with an unfavorable body fat distribution and increased glucose and insulin concentrations and insulin resistance in both pre-and postmenopausal women. However, the temporal direction of the association between androgens and insulin is uncertain. In men, the association between SHBG and insulin levels is much weaker and is probably inverse.
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