Specific oral tolerance induction in children with very severe cow's milk–induced reactions

G Longo, E Barbi, I Berti, R Meneghetti, A Pittalis… - Journal of allergy and …, 2008 - Elsevier
BACKGROUND: Some children allergic to cow's milk proteins (CMPs) experience
exceptionally severe reactions after ingesting only trace amounts of antigen. Avoiding the
food and carrying self-injectable epinephrine are the current strategies for their
management. OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of
specific oral tolerance induction (SOTI) for children with severe CMP-induced systemic
reactions. METHODS: Ninety-seven children aged 5 years or older with a history of severe …