Sterol metabolism studies in the rat. Effects of primary bile acids (sodium taurochenodeoxycholate and sodium taurocholate) on sterol metabolism
BI Cohen, RF Raicht, EH Mosbach - Journal of Lipid Research, 1977 - ASBMB
Sterol metabolism studies using a combination of isotopic and chromatographic procedures
were carried out in rats fed either a low-cholesterol stock diet or a stock diet containing 0.1%
cholesterol. The primary bile acids, sodium taurochenodeoxycholate and sodium
taurocholate, were added to the stock diets at a level of 0.5%, as required. Feeding sodium
taurochenodeoxycholate and sodium taurocholate led to a decrease in acidic steroid
synthesis, cholesterol turnover, and cholesterol balance, compared to controls. Sodium …
were carried out in rats fed either a low-cholesterol stock diet or a stock diet containing 0.1%
cholesterol. The primary bile acids, sodium taurochenodeoxycholate and sodium
taurocholate, were added to the stock diets at a level of 0.5%, as required. Feeding sodium
taurochenodeoxycholate and sodium taurocholate led to a decrease in acidic steroid
synthesis, cholesterol turnover, and cholesterol balance, compared to controls. Sodium …
