Is the loose anagen hair syndrome a keratin disorder?: A clinical and molecular study
V Chapalain, H Winter, L Langbein… - Archives of …, 2002 - jamanetwork.com
Objectives To report the clinical features of the loose anagen hair syndrome and to test the
hypothesis that the typical gap between the hair and the inner root sheath may result from
hereditary defects in the inner root sheath or the apposed companion layer. Design Case
series. Setting A pediatric dermatology unit (referral center). Patients A consecutive sample
of 17 children (13 girls). For 9 of them and their first-degree relatives, molecular analyses
were performed in theK6HFgene with 50 appropriate controls. Intervention Minoxidil therapy …
hypothesis that the typical gap between the hair and the inner root sheath may result from
hereditary defects in the inner root sheath or the apposed companion layer. Design Case
series. Setting A pediatric dermatology unit (referral center). Patients A consecutive sample
of 17 children (13 girls). For 9 of them and their first-degree relatives, molecular analyses
were performed in theK6HFgene with 50 appropriate controls. Intervention Minoxidil therapy …