[HTML][HTML] Human HDAC7 histone deacetylase activity is associated with HDAC3in vivo
W Fischle, F Dequiedt, M Fillion, MJ Hendzel… - Journal of Biological …, 2001 - ASBMB
Histone deacetylases (HDACs) are part of transcriptional corepressor complexes and play
key roles in regulating chromatin structure. Three different classes of human HDACs have
been defined based on their homology to HDACs found in Saccharomyces cerevisiae:
RPD3 (class I), HDA1 (class II), and SIR2 (class III). Here we describe the identification and
functional characterization of HDAC7, a new member of the human class II HDAC family.
Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm …
key roles in regulating chromatin structure. Three different classes of human HDACs have
been defined based on their homology to HDACs found in Saccharomyces cerevisiae:
RPD3 (class I), HDA1 (class II), and SIR2 (class III). Here we describe the identification and
functional characterization of HDAC7, a new member of the human class II HDAC family.
Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm …
