Spatiotemporal differences in the c-fos pathway between C57BL/6J and DBA/2J mice following flurothyl-induced seizures: a dissociation of hippocampal Fos from …
SB Kadiyala, D Papandrea, K Tuz, TM Anderson… - Epilepsy research, 2015 - Elsevier
Significant differences in seizure characteristics between inbred mouse strains highlight the
importance of genetic predisposition to epilepsy. Here, we examined the genetic differences
between the seizure-resistant C57BL/6J (B6) mouse strain and the seizure-susceptible
DBA/2J (D2) strain in the phospho-Erk and Fos pathways to examine seizure-induced
neuronal activity to uncover potential mechanistic correlates to these disparate seizure
responsivities. Expression of neural activity markers was examined following 1, 5, or 8 …
importance of genetic predisposition to epilepsy. Here, we examined the genetic differences
between the seizure-resistant C57BL/6J (B6) mouse strain and the seizure-susceptible
DBA/2J (D2) strain in the phospho-Erk and Fos pathways to examine seizure-induced
neuronal activity to uncover potential mechanistic correlates to these disparate seizure
responsivities. Expression of neural activity markers was examined following 1, 5, or 8 …
