Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain

MFM Hoekman, FMJ Jacobs, MP Smidt… - Gene Expression …, 2006 - Elsevier
In order to obtain leads to molecular mechanisms of signal transduction pathways and
controled gene expression in neuronal development we have screened the adult mouse
brain for expressed forkhead transcription factors using a degenerate RT-PCR approach.
Here, we focus on three FoxO genes found to be expressed in the brain: FoxO1, FoxO3 and
FoxO6. The FoxO subfamily of forkhead transcription family is emerging as a central
keypoint in an array of cellular functions, such as metabolism, differentiation and …