Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents
PV Belichenko, A Oldfors, B Hagberg, A Dahlström - Neuroreport, 1994 - journals.lww.com
Autopsy material from three patients with Rett syndrome and six control cases (frontal,
temporal and motor cortical areas) were studied. Pyramidal and non-pyramidal neurones,
100–200 in each specimen, were visualized by Lucifer Yellow microinjection. 3-D
reconstructions and rotations were computed using the VoxelView/GT program. Various
types of abnormalities in 3-D dendritic architecture of pyramidal neurones in different
cortices were observed. Some pyramidal cells in layers II-III had a subnormal number of …
temporal and motor cortical areas) were studied. Pyramidal and non-pyramidal neurones,
100–200 in each specimen, were visualized by Lucifer Yellow microinjection. 3-D
reconstructions and rotations were computed using the VoxelView/GT program. Various
types of abnormalities in 3-D dendritic architecture of pyramidal neurones in different
cortices were observed. Some pyramidal cells in layers II-III had a subnormal number of …