Myocardin-related transcription factor A (MRTFA) is a coactivator of serum response factor, a
transcription factor that participates in several critical cellular functions including cell growth
and apoptosis. MRTFA couples transcriptional regulation to actin cytoskeleton dynamics,
and the transcriptional targets of the MRTFA–serum response factor complex include genes
encoding cytoskeletal proteins as well as immediate early genes. Previous work has shown
that MRTFA promotes the differentiation of many cell types, including various types of …