[HTML][HTML] Two novel members of the ABLIM protein family, ABLIM-2 and-3, associate with STARS and directly bind F-actin
T Barrientos, D Frank, K Kuwahara… - Journal of biological …, 2007 - ASBMB
In addition to regulating cell motility, contractility, and cytokinesis, the actin cytoskeleton
plays a critical role in the regulation of transcription and gene expression. We have
previously identified a novel muscle-specific actin-binding protein, STARS (striated muscle
activator of Rho signaling), which directly binds actin and stimulates serum-response factor
(SRF)-dependent transcription. To further dissect the STARS/SRF pathway, we performed a
yeast two-hybrid screen of a skeletal muscle cDNA library using STARS as bait, and we …
plays a critical role in the regulation of transcription and gene expression. We have
previously identified a novel muscle-specific actin-binding protein, STARS (striated muscle
activator of Rho signaling), which directly binds actin and stimulates serum-response factor
(SRF)-dependent transcription. To further dissect the STARS/SRF pathway, we performed a
yeast two-hybrid screen of a skeletal muscle cDNA library using STARS as bait, and we …
